extreme antibiotic resistant acinetobacter baumannii-related pneumonia in a regional hospital

نویسندگان

enayatollah kalantar

department of microbiology and immunology, school of medicine, alborz university of medical sciences, karaj, ir iran. ali kurd

deputy of treatment, alborz university of medical sciences, karaj, ir iran. kourosh kabir

department of social medicine, school of medicine, alborz university of medical sciences, karaj, ir iran. parviz afrogh

department of mycobacterium and pulmonary, institute of pasteur of iran, tehran, ir iran. sara mohammadi

چکیده

most nosocomial infections have been attributed to nonfermenters, particularly acinetobacter baumannii which causes serious infections like pneumonia, meningitis, and sepsis. the purpose of this study was to report our experience with five cases of a. baumannii-related pneumonia infections, seen in a regional hospital, karaj, iran. five cases were identified as having a. baumannii- related pneumonia infection.  all cases had been treated previously with various antibiotics at time of diagnosis. the treatment of a. baumannii- related pneumonia infection in all the cases varied. but unfortunately, all the five cases died from severe a. baumannii- related pneumonia and severe sepsis. our cases brought forth the burden of a. baumannii-related pneumonia infections associated with significant mortality. physicians should be aware of the remarkable virulence and antibiotic resistance.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antibiotic combinations for serious infections caused by carbapenem-resistant Acinetobacter baumannii in a mouse pneumonia model.

OBJECTIVES Successful therapy of carbapenem-resistant Acinetobacter baumannii strains has been reported with colistin, but recently we argued against its use as monotherapy because of the poor results obtained in a mouse pneumonia model. Our aim was to identify antibiotic combinations that were valid therapeutic alternatives in the same model. METHODS We used two carbapenem-resistant A. bauma...

متن کامل

Termination of an Extreme-Drug Resistant-Acinetobacter baumannii Outbreak in a Hospital After Flooding: Lessons Learned.

TO THE EDITOR—Outbreaks of extremedrug resistant (XDR)–Acinetobacter baumannii have occurred in several parts of the world and are associated with increased morbidity, mortality and healthcare resource utilization [1–3]. Termination of an outbreak can be challenging in a resource-limited setting, given the lack of infection prevention infrastructure and staff [4]. Little information is availabl...

متن کامل

Carbapenem-resistant Acinetobacter baumannii

To the editor: We read with interest the paper of Hrabák et al. [1] on the isolation of a blaNDM-1-carrying Acinetobacter baumannii strain. However, although the authors believed to be the first in the Czech Republic to report on a New Delhi metallo-beta-lactamase-1 (NDM-1)-producing bacterium, there have been other reports on the same A. baumannii strain in the country [2,3]. Here, we would li...

متن کامل

Multidrug-Resistant Acinetobacter baumannii

To understand the epidemiology of multidrug-resistant (MDR) Acinetobacter baumannii and define individual risk factors for multidrug resistance, we used epidemiologic methods, performed organism typing by pulsed-field gel electrophoresis (PFGE), and conducted a matched case-control retrospective study. We investigated 118 patients, on 27 wards in Israel, in whom MDR A. baumannii was isolated fr...

متن کامل

Biofilm-Related Genes: Analyses in Multi-Antibiotic Resistant Acinetobacter Baumannii Isolates From Mainland China

BACKGROUND Acinetobacter baumannii is an important nosocomial pathogen which shows a high level of mortality risk. Several papers have reported biofilm formation as a well-known pathogenic mechanism in A. baumannii infections and exceptional antibiotic resistance. The study aims to explore the potential relationships between biofilm-related genes and antimicrobial resistance. MATERIAL AND METHO...

متن کامل

Multidrug-Resistant Acinetobacter baumannii

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 13, No. 6, June 2007 943 single-source exposure with C. botulinum type B in at least 3 IDUs; this implies that the heroin was obtained from a common source, where contamination with C. botulinum spores may have been introduced when mixed with adulterants or diluted with substances such as dextrose or dyed paper. Skin popping (subcutaneous an...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
infection, epidemiology and medicine

جلد ۲، شماره ۴، صفحات ۲۹-۳۱

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023